While treatment advances have improved overall survival in some metastatic breast cancer (mBC) subtypes, there remains no cure for mBC. Considering the use of progression-free survival and other surrogate endpoints in clinical trials, it’s useful to understand patient perspectives on measures used to assess treatment efficacy. Precision’s Suepattra May-Slater co-authored an important paper exploring global patient perceptions and their potential relation to quality of life, identifying considerations for the design and conduct of future clinical trials in mBC, as well as HTA and reimbursement decision-making, to better capture the potential value of a therapeutic innovation.